Development of Lipidoid Nanoparticles for siRNA Delivery to Neural Cells
Development of Lipidoid Nanoparticles for siRNA Delivery to Neural Cells
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Publisher
United States: Springer
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Language
English
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Publisher
United States: Springer
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Contents
Lipidoid nanoparticles (LNPs) are the delivery platform in Onpattro, the first FDA-approved siRNA drug. LNPs are also the carriers in the Pfizer-BioNTech and Moderna COVID-19 mRNA vaccines. While these applications have demonstrated that LNPs effectively deliver nucleic acids to hepatic and muscle cells, it is unclear if LNPs could be used for deli...
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Full title
Development of Lipidoid Nanoparticles for siRNA Delivery to Neural Cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8648339
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8648339
Other Identifiers
ISSN
1550-7416
E-ISSN
1550-7416
DOI
10.1208/s12248-021-00653-2
