An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, f...
An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging
About this item
Full title
Author / Creator
Sayed, Nazish , Huang, Yingxiang , Nguyen, Khiem , Krejciova-Rajaniemi, Zuzana , Grawe, Anissa P. , Gao, Tianxiang , Tibshirani, Robert , Hastie, Trevor , Alpert, Ayelet , Cui, Lu , Kuznetsova, Tatiana , Rosenberg-Hasson, Yael , Ostan, Rita , Monti, Daniela , Lehallier, Benoit , Shen-Orr, Shai S. , Maecker, Holden T. , Dekker, Cornelia L. , Wyss-Coray, Tony , Franceschi, Claudio , Jojic, Vladimir , Haddad, François , Montoya, José G. , Wu, Joseph C. , Davis, Mark M. and Furman, David
Publisher
United States: Nature Publishing Group
Journal title
Language
English
Formats
Publication information
Publisher
United States: Nature Publishing Group
Subjects
More information
Scope and Contents
Contents
While many diseases of aging have been linked to the immunological system, immune metrics capable of identifying the most at-risk individuals are lacking. From the blood immunome of 1,001 individuals aged 8-96 years, we developed a deep-learning method based on patterns of systemic age-related inflammation. The resulting inflammatory clock of aging...
Alternative Titles
Full title
An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging
Authors, Artists and Contributors
Author / Creator
Huang, Yingxiang
Nguyen, Khiem
Krejciova-Rajaniemi, Zuzana
Grawe, Anissa P.
Gao, Tianxiang
Tibshirani, Robert
Hastie, Trevor
Alpert, Ayelet
Cui, Lu
Kuznetsova, Tatiana
Rosenberg-Hasson, Yael
Ostan, Rita
Monti, Daniela
Lehallier, Benoit
Shen-Orr, Shai S.
Maecker, Holden T.
Dekker, Cornelia L.
Wyss-Coray, Tony
Franceschi, Claudio
Jojic, Vladimir
Haddad, François
Montoya, José G.
Wu, Joseph C.
Davis, Mark M.
Furman, David
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8654267
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8654267
Other Identifiers
ISSN
2662-8465
E-ISSN
2662-8465
DOI
10.1038/s43587-021-00082-y
