TTPAL promotes gastric tumorigenesis by directly targeting NNMT to activate PI3K/AKT signaling
TTPAL promotes gastric tumorigenesis by directly targeting NNMT to activate PI3K/AKT signaling
About this item
Full title
Author / Creator
Liu, Wenxiu , Gou, Hongyan , Wang, Xiaohong , Li, Xiaoming , Hu, Xiaoxu , Su, Hao , Li, Shengmian and Yu, Jun
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Copy number alterations are crucial for gastric cancer (GC) development. In this study, Tocopherol alpha transfer protein-like (TTPAL) was identified to be highly amplified in our primary GC cohort (30/86). Multivariate analysis showed that high TTPAL expression was correlated with the poor prognosis of GC patients. Ectopic expression of TTPAL prom...
Alternative Titles
Full title
TTPAL promotes gastric tumorigenesis by directly targeting NNMT to activate PI3K/AKT signaling
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8660633
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8660633
Other Identifiers
ISSN
0950-9232,1476-5594
E-ISSN
1476-5594
DOI
10.1038/s41388-021-01838-x
