PI3K-driven HER2 expression is a potential therapeutic target in colorectal cancer stem cells
PI3K-driven HER2 expression is a potential therapeutic target in colorectal cancer stem cells
About this item
Full title
Author / Creator
Mangiapane, Laura Rosa , Nicotra, Annalisa , Turdo, Alice , Gaggianesi, Miriam , Bianca, Paola , Di Franco, Simone , Sardina, Davide Stefano , Veschi, Veronica , Signore, Michele , Beyes, Sven , Fagnocchi, Luca , Fiori, Micol Eleonora , Bongiorno, Maria Rita , Lo Iacono, Melania , Pillitteri, Irene , Ganduscio, Gloria , Gulotta, Gaspare , Medema, Jan Paul , Zippo, Alessio , Todaro, Matilde , De Maria, Ruggero and Stassi, Giorgio
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Subjects
More information
Scope and Contents
Contents
ObjectiveCancer stem cells are responsible for tumour spreading and relapse. Human epidermal growth factor receptor 2 (HER2) expression is a negative prognostic factor in colorectal cancer (CRC) and a potential target in tumours carrying the gene amplification. Our aim was to define the expression of HER2 in colorectal cancer stem cells (CR-CSCs) a...
Alternative Titles
Full title
PI3K-driven HER2 expression is a potential therapeutic target in colorectal cancer stem cells
Authors, Artists and Contributors
Author / Creator
Nicotra, Annalisa
Turdo, Alice
Gaggianesi, Miriam
Bianca, Paola
Di Franco, Simone
Sardina, Davide Stefano
Veschi, Veronica
Signore, Michele
Beyes, Sven
Fagnocchi, Luca
Fiori, Micol Eleonora
Bongiorno, Maria Rita
Lo Iacono, Melania
Pillitteri, Irene
Ganduscio, Gloria
Gulotta, Gaspare
Medema, Jan Paul
Zippo, Alessio
Todaro, Matilde
De Maria, Ruggero
Stassi, Giorgio
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8666826
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8666826
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2020-323553
