Structure and function of retroviral integrase
Structure and function of retroviral integrase
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
A hallmark of retroviral replication is establishment of the proviral state, wherein a DNA copy of the viral RNA genome is stably incorporated into a host cell chromosome. Integrase is the viral enzyme responsible for the catalytic steps involved in this process, and integrase strand transfer inhibitors are widely used to treat people living with H...
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Full title
Structure and function of retroviral integrase
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8671357
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8671357
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ISSN
1740-1526
E-ISSN
1740-1534
DOI
10.1038/s41579-021-00586-9