Kynurenic acid in neurodegenerative disorders—unique neuroprotection or double‐edged sword?
Kynurenic acid in neurodegenerative disorders—unique neuroprotection or double‐edged sword?
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Publisher
England: John Wiley & Sons, Inc
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Language
English
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Publisher
England: John Wiley & Sons, Inc
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Aims
The family of kynurenine pathway (KP) metabolites includes compounds produced along two arms of the path and acting in clearly opposite ways. The equilibrium between neurotoxic kynurenines, such as 3‐hydroxykynurenine (3‐HK) or quinolinic acid (QUIN), and neuroprotective kynurenic acid (KYNA) profoundly impacts the function and survival of...
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Full title
Kynurenic acid in neurodegenerative disorders—unique neuroprotection or double‐edged sword?
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8673711
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8673711
Other Identifiers
ISSN
1755-5930,1755-5949
E-ISSN
1755-5949
DOI
10.1111/cns.13768
