Enhanced detection of minimal residual disease by targeted sequencing of phased variants in circulat...
Enhanced detection of minimal residual disease by targeted sequencing of phased variants in circulating tumor DNA
About this item
Full title
Author / Creator
Kurtz, David M. , Soo, Joanne , Co Ting Keh, Lyron , Alig, Stefan , Chabon, Jacob J. , Sworder, Brian J. , Schultz, Andre , Jin, Michael C. , Scherer, Florian , Garofalo, Andrea , Macaulay, Charles W. , Hamilton, Emily G. , Chen, Binbin , Olsen, Mari , Schroers-Martin, Joseph G. , Craig, Alexander F. M. , Moding, Everett J. , Esfahani, Mohammad S. , Liu, Chih Long , Dührsen, Ulrich , Hüttmann, Andreas , Casasnovas, René-Olivier , Westin, Jason R. , Roschewski, Mark , Wilson, Wyndham H. , Gaidano, Gianluca , Rossi, Davide , Diehn, Maximilian and Alizadeh, Ash A.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Circulating tumor-derived DNA (ctDNA) is an emerging biomarker for many cancers, but the limited sensitivity of current detection methods reduces its utility for diagnosing minimal residual disease. Here we describe phased variant enrichment and detection sequencing (PhasED-seq), a method that uses multiple somatic mutations in individual DNA fragm...
Alternative Titles
Full title
Enhanced detection of minimal residual disease by targeted sequencing of phased variants in circulating tumor DNA
Authors, Artists and Contributors
Author / Creator
Soo, Joanne
Co Ting Keh, Lyron
Alig, Stefan
Chabon, Jacob J.
Sworder, Brian J.
Schultz, Andre
Jin, Michael C.
Scherer, Florian
Garofalo, Andrea
Macaulay, Charles W.
Hamilton, Emily G.
Chen, Binbin
Olsen, Mari
Schroers-Martin, Joseph G.
Craig, Alexander F. M.
Moding, Everett J.
Esfahani, Mohammad S.
Liu, Chih Long
Dührsen, Ulrich
Hüttmann, Andreas
Casasnovas, René-Olivier
Westin, Jason R.
Roschewski, Mark
Wilson, Wyndham H.
Gaidano, Gianluca
Rossi, Davide
Diehn, Maximilian
Alizadeh, Ash A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8678141
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8678141
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/s41587-021-00981-w
