Targeting protumor factor chitinase-3-like-1 secreted by Rab37 vesicles for cancer immunotherapy
Targeting protumor factor chitinase-3-like-1 secreted by Rab37 vesicles for cancer immunotherapy
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Publisher
Australia: Ivyspring International Publisher Pty Ltd
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Language
English
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Publisher
Australia: Ivyspring International Publisher Pty Ltd
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Scope and Contents
Contents
Chitinase 3-like-1 (CHI3L1) is a secretion glycoprotein associated with the immunosuppressive tumor microenvironment (TME). The secretory mode of CHI3L1 makes it a promising target for cancer treatment. We have previously reported that Rab37 small GTPase mediates secretion of IL-6 in macrophages to promote cancer progression, whereas the roles of R...
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Full title
Targeting protumor factor chitinase-3-like-1 secreted by Rab37 vesicles for cancer immunotherapy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8690922
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8690922
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ISSN
1838-7640
E-ISSN
1838-7640
DOI
10.7150/thno.65522