VX765, a Specific Caspase-1 Inhibitor, Alleviates Lung Ischemia Reperfusion Injury by Suppressing En...
VX765, a Specific Caspase-1 Inhibitor, Alleviates Lung Ischemia Reperfusion Injury by Suppressing Endothelial Pyroptosis and Barrier Dysfunction
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Author / Creator
Wu, Siyi , Li, Zhao , Ye, Mengling , Liu, Chunxia , Liu, Hao , He, Xiaojing , Qin, Yi , Liang, Fangte , Pan, Linghui and Lin, Fei
Publisher
United States: Hindawi
Journal title
Language
English
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Publication information
Publisher
United States: Hindawi
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Scope and Contents
Contents
Lung ischemia reperfusion injury (LIRI) is a complex pathophysiological process with high morbidity and mortality. An important pathophysiological characteristic of LIRI is endothelial barrier dysfunction, although the mechanism involved in this process remains unclear. VX765, a specific caspase-1 inhibitor, has been shown to have a protective effe...
Alternative Titles
Full title
VX765, a Specific Caspase-1 Inhibitor, Alleviates Lung Ischemia Reperfusion Injury by Suppressing Endothelial Pyroptosis and Barrier Dysfunction
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8716216
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8716216
Other Identifiers
ISSN
2314-6133
E-ISSN
2314-6141
DOI
10.1155/2021/4525988
