Molecular characteristics and clinical outcomes of patients with Neurofibromin 1-altered metastatic...
Molecular characteristics and clinical outcomes of patients with Neurofibromin 1-altered metastatic colorectal cancer
About this item
Full title
Author / Creator
Arai, Hiroyuki , Elliott, Andrew , Millstein, Joshua , Xiu, Joanne , Ou, Fang-Shu , Innocenti, Federico , Wang, Jingyuan , Battaglin, Francesca , Jayachandran, Priya , Kawanishi, Natsuko , Soni, Shivani , Zhang, Wu , Sohal, Davendra , Goldberg, Richard M. , Hall, Michael J. , Scott, Aaron J. , Khushman, Mohd , Hwang, Jimmy J. , Lou, Emil , Weinberg, Benjamin A. , Lockhart, Albert Craig , Shields, Anthony Frank , Abraham, Jim P. , Magee, Daniel , Stafford, Phillip , Zhang, Jian , Venook, Alan P. , Korn, W. Michael and Lenz, Heinz-Josef
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Loss-of-function alterations of
Neurofibromin 1
(
NF1
) activate RAS, a driver of colorectal cancer. However, the clinical implications of
NF1
alterations are largely unknown. We performed a comprehensive molecular profiling of
NF1
-mutant colorectal cancer using data from 8150 patients included in a dataset of commercial CL...
Alternative Titles
Full title
Molecular characteristics and clinical outcomes of patients with Neurofibromin 1-altered metastatic colorectal cancer
Authors, Artists and Contributors
Author / Creator
Elliott, Andrew
Millstein, Joshua
Xiu, Joanne
Ou, Fang-Shu
Innocenti, Federico
Wang, Jingyuan
Battaglin, Francesca
Jayachandran, Priya
Kawanishi, Natsuko
Soni, Shivani
Zhang, Wu
Sohal, Davendra
Goldberg, Richard M.
Hall, Michael J.
Scott, Aaron J.
Khushman, Mohd
Hwang, Jimmy J.
Lou, Emil
Weinberg, Benjamin A.
Lockhart, Albert Craig
Shields, Anthony Frank
Abraham, Jim P.
Magee, Daniel
Stafford, Phillip
Zhang, Jian
Venook, Alan P.
Korn, W. Michael
Lenz, Heinz-Josef
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8738154
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8738154
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-021-02074-z
