The Dynamics of β-Amyloid Proteoforms Accumulation in the Brain of a 5xFAD Mouse Model of Alzheimer’...
The Dynamics of β-Amyloid Proteoforms Accumulation in the Brain of a 5xFAD Mouse Model of Alzheimer’s Disease
About this item
Full title
Author / Creator
Bugrova, Anna E. , Strelnikova, Polina A. , Indeykina, Maria I. , Kononikhin, Alexey S. , Zakharova, Natalia V. , Brzhozovskiy, Alexander G. , Barykin, Evgeny P. , Pekov, Stanislav I. , Gavrish, Maria S. , Babaev, Alexey A. , Kosyreva, Anna M. , Morozova, Anna Y. , Degterev, Daniil A. , Mitkevich, Vladimir A. , Popov, Igor A. , Makarov, Alexander A. and Nikolaev, Evgeny N.
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
Alzheimer’s disease (AD) is the leading cause of dementia among the elderly. Neuropathologically, AD is characterized by the deposition of a 39- to 42-amino acid long β-amyloid (Aβ) peptide in the form of senile plaques. Several post-translational modifications (PTMs) in the N-terminal domain have been shown to increase the aggregation and cytotoxi...
Alternative Titles
Full title
The Dynamics of β-Amyloid Proteoforms Accumulation in the Brain of a 5xFAD Mouse Model of Alzheimer’s Disease
Authors, Artists and Contributors
Author / Creator
Strelnikova, Polina A.
Indeykina, Maria I.
Kononikhin, Alexey S.
Zakharova, Natalia V.
Brzhozovskiy, Alexander G.
Barykin, Evgeny P.
Pekov, Stanislav I.
Gavrish, Maria S.
Babaev, Alexey A.
Kosyreva, Anna M.
Morozova, Anna Y.
Degterev, Daniil A.
Mitkevich, Vladimir A.
Popov, Igor A.
Makarov, Alexander A.
Nikolaev, Evgeny N.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8745018
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8745018
Other Identifiers
ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms23010027
