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Benchmarking atlas-level data integration in single-cell genomics

Benchmarking atlas-level data integration in single-cell genomics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8748196

Benchmarking atlas-level data integration in single-cell genomics

About this item

Full title

Benchmarking atlas-level data integration in single-cell genomics

Publisher

New York: Nature Publishing Group US

Journal title

Nature methods, 2022-01, Vol.19 (1), p.41-50

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Single-cell atlases often include samples that span locations, laboratories and conditions, leading to complex, nested batch effects in data. Thus, joint analysis of atlas datasets requires reliable data integration. To guide integration method choice, we benchmarked 68 method and preprocessing combinations on 85 batches of gene expression, chromat...

Alternative Titles

Full title

Benchmarking atlas-level data integration in single-cell genomics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8748196

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8748196

Other Identifiers

ISSN

1548-7091

E-ISSN

1548-7105

DOI

10.1038/s41592-021-01336-8

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