RNA demethylase ALKBH5 promotes tumorigenesis in multiple myeloma via TRAF1-mediated activation of N...
RNA demethylase ALKBH5 promotes tumorigenesis in multiple myeloma via TRAF1-mediated activation of NF-κB and MAPK signaling pathways
About this item
Full title
Author / Creator
Qu, Jianwei , Hou, Yifan , Chen, Qingxiao , Chen, Jing , Li, Yi , Zhang, Enfan , Gu, Huiyao , Xu, Ruyi , Liu, Yang , Cao, Wen , Zhang, Jinna , Cao, Liqin , He, Jingsong and Cai, Zhen
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
N
6
-methyladenosine (m
6
A), an internal modification in mRNA, plays a critical role in regulating gene expression. Dysregulation of m
6
A modifiers promotes oncogenesis through enzymatic functions that disrupt the balance between the deposition and removal of m
6
A modification on critical transcripts. However, the roles o...
Alternative Titles
Full title
RNA demethylase ALKBH5 promotes tumorigenesis in multiple myeloma via TRAF1-mediated activation of NF-κB and MAPK signaling pathways
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8755544
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8755544
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-021-02095-8
