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Chondroitin 6-sulphate is required for neuroplasticity and memory in ageing

Chondroitin 6-sulphate is required for neuroplasticity and memory in ageing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8758471

Chondroitin 6-sulphate is required for neuroplasticity and memory in ageing

About this item

Full title

Chondroitin 6-sulphate is required for neuroplasticity and memory in ageing

Publisher

London: Nature Publishing Group UK

Journal title

Molecular psychiatry, 2021-10, Vol.26 (10), p.5658-5668

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Perineuronal nets (PNNs) are chondroitin sulphate proteoglycan-containing structures on the neuronal surface that have been implicated in the control of neuroplasticity and memory. Age-related reduction of chondroitin 6-sulphates (C6S) leads to PNNs becoming more inhibitory. Here, we investigated whether manipulation of the chondroitin sulphate (CS...

Alternative Titles

Full title

Chondroitin 6-sulphate is required for neuroplasticity and memory in ageing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8758471

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8758471

Other Identifiers

ISSN

1359-4184,1476-5578

E-ISSN

1476-5578

DOI

10.1038/s41380-021-01208-9

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