Hyperpolarized 13C-Pyruvate Metabolism as a Surrogate for Tumor Grade and Poor Outcome in Renal Cell...
Hyperpolarized 13C-Pyruvate Metabolism as a Surrogate for Tumor Grade and Poor Outcome in Renal Cell Carcinoma—A Proof of Principle Study
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Author / Creator
Ursprung, Stephan , Woitek, Ramona , McLean, Mary A. , Priest, Andrew N. , Crispin-Ortuzar, Mireia , Brodie, Cara R. , Gill, Andrew B. , Gehrung, Marcel , Beer, Lucian , Riddick, Antony C. P. , Field-Rayner, Johanna , Grist, James T. , Deen, Surrin S. , Riemer, Frank , Kaggie, Joshua D. , Zaccagna, Fulvio , Duarte, Joao A. G. , Locke, Matthew J. , Frary, Amy , Aho, Tevita F. , Armitage, James N. , Casey, Ruth , Mendichovszky, Iosif A. , Welsh, Sarah J. , Barrett, Tristan , Graves, Martin J. , Eisen, Tim , Mitchell, Thomas J. , Warren, Anne Y. , Brindle, Kevin M. , Sala, Evis , Stewart, Grant D. and Gallagher, Ferdia A.
Publisher
Basel: MDPI AG
Journal title
Language
English
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Publication information
Publisher
Basel: MDPI AG
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More information
Scope and Contents
Contents
Differentiating aggressive clear cell renal cell carcinoma (ccRCC) from indolent lesions is challenging using conventional imaging. This work prospectively compared the metabolic imaging phenotype of renal tumors using carbon-13 MRI following injection of hyperpolarized [1-13C]pyruvate (HP-13C-MRI) and validated these findings with histopathology....
Alternative Titles
Full title
Hyperpolarized 13C-Pyruvate Metabolism as a Surrogate for Tumor Grade and Poor Outcome in Renal Cell Carcinoma—A Proof of Principle Study
Authors, Artists and Contributors
Author / Creator
Woitek, Ramona
McLean, Mary A.
Priest, Andrew N.
Crispin-Ortuzar, Mireia
Brodie, Cara R.
Gill, Andrew B.
Gehrung, Marcel
Beer, Lucian
Riddick, Antony C. P.
Field-Rayner, Johanna
Grist, James T.
Deen, Surrin S.
Riemer, Frank
Kaggie, Joshua D.
Zaccagna, Fulvio
Duarte, Joao A. G.
Locke, Matthew J.
Frary, Amy
Aho, Tevita F.
Armitage, James N.
Casey, Ruth
Mendichovszky, Iosif A.
Welsh, Sarah J.
Barrett, Tristan
Graves, Martin J.
Eisen, Tim
Mitchell, Thomas J.
Warren, Anne Y.
Brindle, Kevin M.
Sala, Evis
Stewart, Grant D.
Gallagher, Ferdia A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8773685
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8773685
Other Identifiers
ISSN
2072-6694
E-ISSN
2072-6694
DOI
10.3390/cancers14020335