Mitotic phosphorylation of tumor suppressor DAB2IP maintains spindle assembly checkpoint and chromos...
Mitotic phosphorylation of tumor suppressor DAB2IP maintains spindle assembly checkpoint and chromosomal stability through activating PLK1-Mps1 signal pathway and stabilizing mitotic checkpoint complex
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Chromosomal instability (CIN) is a driving force for cancer development. The most common causes of CIN include the dysregulation of the spindle assembly checkpoint (SAC), which is a surveillance mechanism that prevents premature chromosome separation during mitosis by targeting anaphase-promoting complex/cyclosome (APC/C). DAB2IP is frequently sile...
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Mitotic phosphorylation of tumor suppressor DAB2IP maintains spindle assembly checkpoint and chromosomal stability through activating PLK1-Mps1 signal pathway and stabilizing mitotic checkpoint complex
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8782720
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8782720
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-021-02106-8
