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SOX10: 20 years of phenotypic plurality and current understanding of its developmental function

SOX10: 20 years of phenotypic plurality and current understanding of its developmental function

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8788258

SOX10: 20 years of phenotypic plurality and current understanding of its developmental function

About this item

Full title

SOX10: 20 years of phenotypic plurality and current understanding of its developmental function

Publisher

England: BMJ Publishing Group Ltd

Journal title

Journal of medical genetics, 2022-02, Vol.59 (2), p.105-114

Language

English

Formats

Publication information

Publisher

England: BMJ Publishing Group Ltd

More information

Scope and Contents

Contents

SOX10 belongs to a family of 20 SRY (sex-determining region Y)-related high mobility group box-containing (SOX) proteins, most of which contribute to cell type specification and differentiation of various lineages. The first clue that SOX10 is essential for development, especially in the neural crest, came with the discovery that heterozygous mutat...

Alternative Titles

Full title

SOX10: 20 years of phenotypic plurality and current understanding of its developmental function

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8788258

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8788258

Other Identifiers

ISSN

0022-2593

E-ISSN

1468-6244

DOI

10.1136/jmedgenet-2021-108105

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