A large fraction of trisomy 12, 17p⁻, and 11q⁻ CLL cases carry unidentified microdeletions of miR-15...
A large fraction of trisomy 12, 17p⁻, and 11q⁻ CLL cases carry unidentified microdeletions of miR-15a/16-1
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Chronic lymphocytic leukemia (CLL) is the most common adult leukemia and is characterized by chromosomal aberrations including 13q, 11q, and 17p deletions and a trisomy of chromosome 12 (T12). 13q deletions are often associated with 11q and 17p deletions in aggressive cases. Conversely, T12 CLLs show a variable prognosis, and association with 13q d...
Alternative Titles
Full title
A large fraction of trisomy 12, 17p⁻, and 11q⁻ CLL cases carry unidentified microdeletions of miR-15a/16-1
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8794880
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8794880
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2118752119
