POLG-related disorders and their neurological manifestations
POLG-related disorders and their neurological manifestations
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The
POLG
gene encodes the mitochondrial DNA polymerase that is responsible for replication of the mitochondrial genome. Mutations in
POLG
can cause early childhood mitochondrial DNA (mtDNA) depletion syndromes or later-onset syndromes arising from mtDNA deletions.
POLG
mutations are the most common cause of inherited mitochondrial...
Alternative Titles
Full title
POLG-related disorders and their neurological manifestations
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8796686
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8796686
Other Identifiers
ISSN
1759-4758,1759-4766
E-ISSN
1759-4766
DOI
10.1038/s41582-018-0101-0
