Efficacy of Antibodies and Antiviral Drugs against Covid-19 Omicron Variant
Efficacy of Antibodies and Antiviral Drugs against Covid-19 Omicron Variant
About this item
Full title
Author / Creator
Takashita, Emi , Kinoshita, Noriko , Yamayoshi, Seiya , Sakai-Tagawa, Yuko , Fujisaki, Seiichiro , Ito, Mutsumi , Iwatsuki-Horimoto, Kiyoko , Chiba, Shiho , Halfmann, Peter , Nagai, Hiroyuki , Saito, Makoto , Adachi, Eisuke , Sullivan, David , Pekosz, Andrew , Watanabe, Shinji , Maeda, Kenji , Imai, Masaki , Yotsuyanagi, Hiroshi , Mitsuya, Hiroaki , Ohmagari, Norio , Takeda, Makoto , Hasegawa, Hideki and Kawaoka, Yoshihiro
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Investigators assessed the in vitro activities of seven monoclonal antibodies and three antiviral drugs against Covid-19 variants of concern. All the antibodies showed either no or weak neutralizing activity against the omicron variant; two agents that target the RNA polymerase and a protease inhibitor were effective at omicron neutralization.
Alternative Titles
Full title
Efficacy of Antibodies and Antiviral Drugs against Covid-19 Omicron Variant
Authors, Artists and Contributors
Author / Creator
Kinoshita, Noriko
Yamayoshi, Seiya
Sakai-Tagawa, Yuko
Fujisaki, Seiichiro
Ito, Mutsumi
Iwatsuki-Horimoto, Kiyoko
Chiba, Shiho
Halfmann, Peter
Nagai, Hiroyuki
Saito, Makoto
Adachi, Eisuke
Sullivan, David
Pekosz, Andrew
Watanabe, Shinji
Maeda, Kenji
Imai, Masaki
Yotsuyanagi, Hiroshi
Mitsuya, Hiroaki
Ohmagari, Norio
Takeda, Makoto
Hasegawa, Hideki
Kawaoka, Yoshihiro
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8809508
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8809508
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMc2119407
