Immunoglobulin A–specific deficiency induces spontaneous inflammation specifically in the ileum
Immunoglobulin A–specific deficiency induces spontaneous inflammation specifically in the ileum
About this item
Full title
Author / Creator
Nagaishi, Takashi , Watabe, Taro , Kotake, Kunihiko , Kumazawa, Toshihiko , Aida, Tomomi , Tanaka, Kohichi , Ono, Ryuichi , Ishino, Fumitoshi , Usami, Takako , Miura, Takamasa , Hirakata, Satomi , Kawasaki, Hiroko , Tsugawa, Naoya , Yamada, Daiki , Hirayama, Kazuhiro , Yoshikawa, Soichiro , Karasuyama, Hajime , Okamoto, Ryuichi , Watanabe, Mamoru , Blumberg, Richard S and Adachi, Takahiro
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Subjects
More information
Scope and Contents
Contents
ObjectiveAlthough immunoglobulin A (IgA) is abundantly expressed in the gut and known to be an important component of mucosal barriers against luminal pathogens, its precise function remains unclear. Therefore, we tried to elucidate the effect of IgA on gut homeostasis maintenance and its mechanism.DesignWe generated various IgA mutant mouse lines...
Alternative Titles
Full title
Immunoglobulin A–specific deficiency induces spontaneous inflammation specifically in the ileum
Authors, Artists and Contributors
Author / Creator
Watabe, Taro
Kotake, Kunihiko
Kumazawa, Toshihiko
Aida, Tomomi
Tanaka, Kohichi
Ono, Ryuichi
Ishino, Fumitoshi
Usami, Takako
Miura, Takamasa
Hirakata, Satomi
Kawasaki, Hiroko
Tsugawa, Naoya
Yamada, Daiki
Hirayama, Kazuhiro
Yoshikawa, Soichiro
Karasuyama, Hajime
Okamoto, Ryuichi
Watanabe, Mamoru
Blumberg, Richard S
Adachi, Takahiro
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8809603
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8809603
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2020-322873
