G-protein activation by a metabotropic glutamate receptor
G-protein activation by a metabotropic glutamate receptor
About this item
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Author / Creator
Seven, Alpay B. , Barros-Álvarez, Ximena , de Lapeyrière, Marine , Papasergi-Scott, Makaía M. , Robertson, Michael J. , Zhang, Chensong , Nwokonko, Robert M. , Gao, Yang , Meyerowitz, Justin G. , Rocher, Jean-Philippe , Schelshorn, Dominik , Kobilka, Brian K. , Mathiesen, Jesper M. and Skiniotis, Georgios
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Family C G-protein-coupled receptors (GPCRs) operate as obligate dimers with extracellular domains that recognize small ligands, leading to G-protein activation on the transmembrane (TM) domains of these receptors by an unknown mechanism
1
. Here we show structures of homodimers of the family C metabotropic glutamate receptor 2 (mGlu2) in dis...
Alternative Titles
Full title
G-protein activation by a metabotropic glutamate receptor
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8822903
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8822903
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-021-03680-3
