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Functional and structural basis of extreme conservation in vertebrate 5′ untranslated regions

Functional and structural basis of extreme conservation in vertebrate 5′ untranslated regions

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8825242

Functional and structural basis of extreme conservation in vertebrate 5′ untranslated regions

About this item

Full title

Functional and structural basis of extreme conservation in vertebrate 5′ untranslated regions

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2021-05, Vol.53 (5), p.729-741

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The lack of knowledge about extreme conservation in genomes remains a major gap in our understanding of the evolution of gene regulation. Here, we reveal an unexpected role of extremely conserved 5′ untranslated regions (UTRs) in noncanonical translational regulation that is linked to the emergence of essential developmental features in vertebrate...

Alternative Titles

Full title

Functional and structural basis of extreme conservation in vertebrate 5′ untranslated regions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8825242

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8825242

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/s41588-021-00830-1

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