Asymmetric activation of the calcium-sensing receptor homodimer
Asymmetric activation of the calcium-sensing receptor homodimer
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The calcium-sensing receptor (CaSR), a cell-surface sensor for Ca
2+
, is the master regulator of calcium homeostasis in humans and is the target of calcimimetic drugs for the treatment of parathyroid disorders
1
. CaSR is a family C G-protein-coupled receptor
2
that functions as an obligate homodimer, with each protomer composed...
Alternative Titles
Full title
Asymmetric activation of the calcium-sensing receptor homodimer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8826748
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8826748
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-021-03691-0