Plasma-Derived Hemopexin as a Candidate Therapeutic Agent for Acute Vaso-Occlusion in Sickle Cell Di...
Plasma-Derived Hemopexin as a Candidate Therapeutic Agent for Acute Vaso-Occlusion in Sickle Cell Disease: Preclinical Evidence
About this item
Full title
Author / Creator
Gentinetta, Thomas , Belcher, John D , Brügger-Verdon, Valérie , Adam, Jacqueline , Ruthsatz, Tanja , Bain, Joseph , Schu, Daniel , Ventrici, Lisa , Edler, Monika , Lioe, Hadi , Patel, Kalpeshkumar , Chen, Chunsheng , Nguyen, Julia , Abdulla, Fuad , Zhang, Ping , Wassmer, Andreas , Jain, Meena , Mischnik, Marcel , Pelzing, Matthias , Martin, Kirstee , Davis, Roslyn , Didichenko, Svetlana , Schaub, Alexander , Brinkman, Nathan , Herzog, Eva , Zürcher, Adrian , Vercellotti, Gregory M , Kato, Gregory J and Höbarth, Gerald
Publisher
Switzerland: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: MDPI AG
Subjects
More information
Scope and Contents
Contents
People living with sickle cell disease (SCD) face intermittent acute pain episodes due to vaso-occlusion primarily treated palliatively with opioids. Hemolysis of sickle erythrocytes promotes release of heme, which activates inflammatory cell adhesion proteins on endothelial cells and circulating cells, promoting vaso-occlusion. In this study, plas...
Alternative Titles
Full title
Plasma-Derived Hemopexin as a Candidate Therapeutic Agent for Acute Vaso-Occlusion in Sickle Cell Disease: Preclinical Evidence
Authors, Artists and Contributors
Author / Creator
Belcher, John D
Brügger-Verdon, Valérie
Adam, Jacqueline
Ruthsatz, Tanja
Bain, Joseph
Schu, Daniel
Ventrici, Lisa
Edler, Monika
Lioe, Hadi
Patel, Kalpeshkumar
Chen, Chunsheng
Nguyen, Julia
Abdulla, Fuad
Zhang, Ping
Wassmer, Andreas
Jain, Meena
Mischnik, Marcel
Pelzing, Matthias
Martin, Kirstee
Davis, Roslyn
Didichenko, Svetlana
Schaub, Alexander
Brinkman, Nathan
Herzog, Eva
Zürcher, Adrian
Vercellotti, Gregory M
Kato, Gregory J
Höbarth, Gerald
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8836474
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8836474
Other Identifiers
ISSN
2077-0383
E-ISSN
2077-0383
DOI
10.3390/jcm11030630
