CRISPR and biochemical screens identify MAZ as a cofactor in CTCF-mediated insulation at Hox cluster...
CRISPR and biochemical screens identify MAZ as a cofactor in CTCF-mediated insulation at Hox clusters
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Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
CCCTC-binding factor (CTCF) is critical to three-dimensional genome organization. Upon differentiation, CTCF insulates active and repressed genes within
Hox
gene clusters. We conducted a genome-wide CRISPR knockout (KO) screen to identify genes required for CTCF-boundary activity at the
HoxA
cluster, complemented by biochemical approach...
Alternative Titles
Full title
CRISPR and biochemical screens identify MAZ as a cofactor in CTCF-mediated insulation at Hox clusters
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8837555
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8837555
Other Identifiers
ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/s41588-021-01008-5
