PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorder...
PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorders
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Publisher
Cham: Springer International Publishing
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Language
English
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Publisher
Cham: Springer International Publishing
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Scope and Contents
Contents
Mutations in the adaptor protein PSTPIP1 cause a spectrum of autoinflammatory diseases, including PAPA and PAMI; however, the mechanism underlying these diseases remains unknown. Most of these mutations lie in PSTPIP1 F-BAR domain, which binds to LYP, a protein tyrosine phosphatase associated with arthritis and lupus. To shed light on the mechanism...
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Full title
PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorders
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8840930
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8840930
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ISSN
1420-682X
E-ISSN
1420-9071
DOI
10.1007/s00018-022-04173-w
