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Controlling the polarity of human gastrointestinal organoids to investigate epithelial biology and i...

Controlling the polarity of human gastrointestinal organoids to investigate epithelial biology and i...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8841224

Controlling the polarity of human gastrointestinal organoids to investigate epithelial biology and infectious diseases

About this item

Full title

Controlling the polarity of human gastrointestinal organoids to investigate epithelial biology and infectious diseases

Publisher

London: Nature Publishing Group UK

Journal title

Nature protocols, 2021-11, Vol.16 (11), p.5171-5192

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Human epithelial organoids—3D spheroids derived from adult tissue stem cells—enable investigation of epithelial physiology and disease and host interactions with microorganisms, viruses and bioactive molecules. One challenge in using organoids is the difficulty in accessing the apical, or luminal, surface of the epithelium, which is enclosed within...

Alternative Titles

Full title

Controlling the polarity of human gastrointestinal organoids to investigate epithelial biology and infectious diseases

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8841224

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8841224

Other Identifiers

ISSN

1754-2189,1750-2799

E-ISSN

1750-2799

DOI

10.1038/s41596-021-00607-0

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