Controlling the polarity of human gastrointestinal organoids to investigate epithelial biology and i...
Controlling the polarity of human gastrointestinal organoids to investigate epithelial biology and infectious diseases
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Human epithelial organoids—3D spheroids derived from adult tissue stem cells—enable investigation of epithelial physiology and disease and host interactions with microorganisms, viruses and bioactive molecules. One challenge in using organoids is the difficulty in accessing the apical, or luminal, surface of the epithelium, which is enclosed within...
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Full title
Controlling the polarity of human gastrointestinal organoids to investigate epithelial biology and infectious diseases
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8841224
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8841224
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ISSN
1754-2189,1750-2799
E-ISSN
1750-2799
DOI
10.1038/s41596-021-00607-0