Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA
Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Clustered somatic mutations are common in cancer genomes and previous analyses reveal several types of clustered single-base substitutions, which include doublet- and multi-base substitutions
1
–
5
, diffuse hypermutation termed omikli
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, and longer strand-coordinated events termed kataegis
3
,
7
–
9
. Here we p...
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Full title
Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8850194
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8850194
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ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-022-04398-6
