The use of Bayesian methodology in the development and validation of a tiered assessment approach to...
The use of Bayesian methodology in the development and validation of a tiered assessment approach towards prediction of rat acute oral toxicity
About this item
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Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Scope and Contents
Contents
There exists consensus that the traditional means by which safety of chemicals is assessed—namely through reliance upon apical outcomes obtained following in vivo testing—is increasingly unfit for purpose. Whilst efforts in development of suitable alternatives continue, few have achieved levels of robustness required for regulatory acceptance. An a...
Alternative Titles
Full title
The use of Bayesian methodology in the development and validation of a tiered assessment approach towards prediction of rat acute oral toxicity
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8850222
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8850222
Other Identifiers
ISSN
0340-5761,1432-0738
E-ISSN
1432-0738
DOI
10.1007/s00204-021-03205-x
