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Modulation of OPRM1 Alternative Splicing by Morphine and HIV–1 Nef

Modulation of OPRM1 Alternative Splicing by Morphine and HIV–1 Nef

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8859008

Modulation of OPRM1 Alternative Splicing by Morphine and HIV–1 Nef

About this item

Full title

Modulation of OPRM1 Alternative Splicing by Morphine and HIV–1 Nef

Publisher

New York: Springer US

Journal title

Journal of neuroimmune pharmacology, 2022-06, Vol.17 (1-2), p.277-288

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Clinically used opioids, such as morphine, activate the mu opioid receptor (MOR) encoded by Opioid Receptor Mu 1 (OPRM1) gene. Examination of the opioid receptor genes showed that the human OPRM1 pre–mRNA undergoes extensive alternative splicing events and capable of expressing 21 isoforms. However, characterization of OPRM1 signaling is generalize...

Alternative Titles

Full title

Modulation of OPRM1 Alternative Splicing by Morphine and HIV–1 Nef

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8859008

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8859008

Other Identifiers

ISSN

1557-1890

E-ISSN

1557-1904

DOI

10.1007/s11481-021-10009-4

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