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Helicobacter pylori infection has a detrimental impact on the efficacy of cancer immunotherapies

Helicobacter pylori infection has a detrimental impact on the efficacy of cancer immunotherapies

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8862014

Helicobacter pylori infection has a detrimental impact on the efficacy of cancer immunotherapies

About this item

Full title

Helicobacter pylori infection has a detrimental impact on the efficacy of cancer immunotherapies

Publisher

England: BMJ Publishing Group Ltd and British Society of Gastroenterology

Journal title

Gut, 2022-03, Vol.71 (3), p.457-466

Language

English

Formats

Publication information

Publisher

England: BMJ Publishing Group Ltd and British Society of Gastroenterology

More information

Scope and Contents

Contents

ObjectiveIn this study, we determined whether Helicobacter pylori (H. pylori) infection dampens the efficacy of cancer immunotherapies.DesignUsing mouse models, we evaluated whether immune checkpoint inhibitors or vaccine-based immunotherapies are effective in reducing tumour volumes of H. pylori-infected mice. In humans, we evaluated the correlati...

Alternative Titles

Full title

Helicobacter pylori infection has a detrimental impact on the efficacy of cancer immunotherapies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8862014

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8862014

Other Identifiers

ISSN

0017-5749

E-ISSN

1468-3288

DOI

10.1136/gutjnl-2020-323392

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