Mitochondrial dysfunction and oxidative stress contribute to cognitive and motor impairment in FOXP1...
Mitochondrial dysfunction and oxidative stress contribute to cognitive and motor impairment in FOXP1 syndrome
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
FOXP1 syndrome caused by haploinsufficiency of the forkhead box protein P1 (FOXP1) gene is a neurodevelopmental disorder that manifests motor dysfunction, intellectual disability, autism, and language impairment. In this study, we used a Foxp1
+/− mouse model to address whether cognitive and motor deficits in FOXP1 syndrome are associated with m...
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Full title
Mitochondrial dysfunction and oxidative stress contribute to cognitive and motor impairment in FOXP1 syndrome
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8872729
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8872729
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2112852119