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Absent in Melanoma 2 (AIM2) Regulates the Stability of Regulatory T Cells

Absent in Melanoma 2 (AIM2) Regulates the Stability of Regulatory T Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8876789

Absent in Melanoma 2 (AIM2) Regulates the Stability of Regulatory T Cells

About this item

Full title

Absent in Melanoma 2 (AIM2) Regulates the Stability of Regulatory T Cells

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2022-02, Vol.23 (4), p.2230

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Absent in melanoma 2 (AIM2) is a cytosolic dsDNA sensor that has been broadly studied for its role in inflammasome assembly. However, little is known about the function of AIM2 in adaptive immune cells. The purpose of this study was to investigate whether AIM2 has a cell-intrinsic role in CD4+ T cell differentiation or function. We found that AIM2...

Alternative Titles

Full title

Absent in Melanoma 2 (AIM2) Regulates the Stability of Regulatory T Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8876789

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8876789

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms23042230

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