PACS2–TRPV1 axis is required for ER–mitochondrial tethering during ER stress and lung fibrosis
PACS2–TRPV1 axis is required for ER–mitochondrial tethering during ER stress and lung fibrosis
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Publisher
Cham: Springer International Publishing
Journal title
Language
English
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Publisher
Cham: Springer International Publishing
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Contents
Endoplasmic reticulum (ER) and mitochondria (mito) play a vital role in alveolar type II cell (AEC2) homeostasis and are both stressed in patients with idiopathic pulmonary fibrosis (IPF). Up to now, no data are available with regard to ER–mito cross talk and tethering under conditions of IPF. We here demonstrate that ER–mitochondrial tethering is...
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Full title
PACS2–TRPV1 axis is required for ER–mitochondrial tethering during ER stress and lung fibrosis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8881280
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8881280
Other Identifiers
ISSN
1420-682X
E-ISSN
1420-9071
DOI
10.1007/s00018-022-04189-2
