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Activating BK channels ameliorates vascular smooth muscle calcification through Akt signaling

Activating BK channels ameliorates vascular smooth muscle calcification through Akt signaling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8888620

Activating BK channels ameliorates vascular smooth muscle calcification through Akt signaling

About this item

Full title

Activating BK channels ameliorates vascular smooth muscle calcification through Akt signaling

Publisher

Singapore: Springer Singapore

Journal title

Acta pharmacologica Sinica, 2022-03, Vol.43 (3), p.624-633

Language

English

Formats

Publication information

Publisher

Singapore: Springer Singapore

More information

Scope and Contents

Contents

Vascular calcification (VC) is characterized by pathological depositions of calcium and phosphate in the arteries and veins via an active cell-regulated process, in which vascular smooth muscle cells (VSMCs) transform into osteoblast/chondrocyte-like cells as in bone formation. VC is associated with significant morbidity and mortality in chronic ki...

Alternative Titles

Full title

Activating BK channels ameliorates vascular smooth muscle calcification through Akt signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8888620

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8888620

Other Identifiers

ISSN

1671-4083

E-ISSN

1745-7254

DOI

10.1038/s41401-021-00704-6

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