Functions and consequences of AID/APOBEC-mediated DNA and RNA deamination
Functions and consequences of AID/APOBEC-mediated DNA and RNA deamination
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Scope and Contents
Contents
The AID/APOBEC polynucleotide cytidine deaminases have historically been classified as either DNA mutators or RNA editors based on their first identified nucleic acid substrate preference. DNA mutators can generate functional diversity at antibody genes but also cause genomic instability in cancer. RNA editors can generate informational diversity i...
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Full title
Functions and consequences of AID/APOBEC-mediated DNA and RNA deamination
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8900473
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8900473
Other Identifiers
ISSN
1471-0056
E-ISSN
1471-0064
DOI
10.1038/s41576-022-00459-8