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Pulmonary fibrosis model using micro-CT analyzable human PSC–derived alveolar organoids containing a...

Pulmonary fibrosis model using micro-CT analyzable human PSC–derived alveolar organoids containing a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8907399

Pulmonary fibrosis model using micro-CT analyzable human PSC–derived alveolar organoids containing alveolar macrophage-like cells

About this item

Full title

Pulmonary fibrosis model using micro-CT analyzable human PSC–derived alveolar organoids containing alveolar macrophage-like cells

Publisher

Dordrecht: Springer Netherlands

Journal title

Cell biology and toxicology, 2022-08, Vol.38 (4), p.557-575

Language

English

Formats

Publication information

Publisher

Dordrecht: Springer Netherlands

More information

Scope and Contents

Contents

Human lung organoids (hLOs) are useful for disease modelling and drug screening. However, a lack of immune cells in hLOs limits the recapitulation of in vivo cellular physiology. Here, we generated hLOs containing alveolar macrophage (AMφ)–like cells derived from pluripotent stem cells (PSC). To bridge hLOs with advanced human lung high-resolution...

Alternative Titles

Full title

Pulmonary fibrosis model using micro-CT analyzable human PSC–derived alveolar organoids containing alveolar macrophage-like cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8907399

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8907399

Other Identifiers

ISSN

0742-2091

E-ISSN

1573-6822

DOI

10.1007/s10565-022-09698-1

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