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Lynch-like Syndrome: Potential Mechanisms and Management

Lynch-like Syndrome: Potential Mechanisms and Management

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8909420

Lynch-like Syndrome: Potential Mechanisms and Management

About this item

Full title

Lynch-like Syndrome: Potential Mechanisms and Management

Publisher

Switzerland: MDPI AG

Journal title

Cancers, 2022-02, Vol.14 (5), p.1115

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Lynch syndrome is an autosomal dominant disorder caused by germline mutations in DNA mismatch repair (MMR) system genes, such as MLH1, MSH2, MSH6, or PMS2. It is the most common hereditary colorectal cancer syndrome. Screening is regularly performed by using microsatellite instability (MSI) or immunohistochemistry for the MMR proteins in tumor samp...

Alternative Titles

Full title

Lynch-like Syndrome: Potential Mechanisms and Management

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8909420

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8909420

Other Identifiers

ISSN

2072-6694

E-ISSN

2072-6694

DOI

10.3390/cancers14051115

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