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Restriction of viral gene expression and replication prevents immortalization of human keratinocytes...

Restriction of viral gene expression and replication prevents immortalization of human keratinocytes...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8931373

Restriction of viral gene expression and replication prevents immortalization of human keratinocytes by a beta-human papillomavirus

About this item

Full title

Restriction of viral gene expression and replication prevents immortalization of human keratinocytes by a beta-human papillomavirus

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (11), p.1-8

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Beta-human papillomaviruses (HPV) have been implicated in the development of cutaneous squamous cell cancer (cSCC) in epidermodysplasia verruciformis (EV) patients and organ transplant recipients. In contrast to high-risk (HR) HPV, which cause anogenital and oropharyngeal cancers, immortalizing activity of complete beta-HPV genomes in normal human...

Alternative Titles

Full title

Restriction of viral gene expression and replication prevents immortalization of human keratinocytes by a beta-human papillomavirus

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8931373

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8931373

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.2118930119

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