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Astrocyte-derived interleukin-3 reprograms microglia and limits Alzheimer’s disease

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Astrocyte-derived interleukin-3 reprograms microglia and limits Alzheimer’s disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8934148

Astrocyte-derived interleukin-3 reprograms microglia and limits Alzheimer’s disease

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Contents

Communication within the glial cell ecosystem is essential to neuronal and brain health
1
–
3
. In Alzheimer’s disease, progressive neurodegeneration is characterized by β-amyloid (Aβ) deposition and neurofibrillary tau formation. The influence of glial cells on Aβ and tau accumulation and clearance is poorly understood, despite growing...

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Full title

Astrocyte-derived interleukin-3 reprograms microglia and limits Alzheimer’s disease

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Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8934148

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8934148

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-021-03734-6

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