COVID-19 microthrombosis: unusually large VWF multimers are a platform for activation of the alterna...
COVID-19 microthrombosis: unusually large VWF multimers are a platform for activation of the alternative complement pathway under cytokine storm
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Publisher
Singapore: Springer Singapore
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Language
English
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Publisher
Singapore: Springer Singapore
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Contents
ADAMTS13, a metalloproteinase, specifically cleaves unusually large multimers of von Willebrand factor (VWF), newly released from vascular endothelial cells. The ratio of ADAMTS13 activity to VWF antigen (ADAMTS13/VWF) and indicators of the alternative complement pathway (C3a and sC5b-9) are both related to the severity of COVID-19. The ADAMTS13/VW...
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Full title
COVID-19 microthrombosis: unusually large VWF multimers are a platform for activation of the alternative complement pathway under cytokine storm
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8938647
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8938647
Other Identifiers
ISSN
0925-5710
E-ISSN
1865-3774
DOI
10.1007/s12185-022-03324-w
