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Ribosomal RNA 2′-O-methylations regulate translation by impacting ribosome dynamics

Ribosomal RNA 2′-O-methylations regulate translation by impacting ribosome dynamics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8944910

Ribosomal RNA 2′-O-methylations regulate translation by impacting ribosome dynamics

About this item

Full title

Ribosomal RNA 2′-O-methylations regulate translation by impacting ribosome dynamics

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (12), p.1-11

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Protein synthesis by ribosomes is critically important for gene expression in all cells. Ribosomal RNAs (rRNAs) are marked by numerous chemical modifications. An abundant group of rRNA modifications, present in all domains of life, is 2′-O-methylation guided by box C/D small nucleolar RNAs, which are part of small ribonucleoprotein complexes (snoRN...

Alternative Titles

Full title

Ribosomal RNA 2′-O-methylations regulate translation by impacting ribosome dynamics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8944910

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8944910

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.2117334119

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