Complex of HIV-1 Integrase with Cellular Ku Protein: Interaction Interface and Search for Inhibitors
Complex of HIV-1 Integrase with Cellular Ku Protein: Interaction Interface and Search for Inhibitors
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
The interaction of HIV-1 integrase and the cellular Ku70 protein is necessary for HIV replication due to its positive effect on post-integration DNA repair. We have previously described in detail the Ku70 binding site within integrase. However, the integrase binding site in Ku70 remained poorly characterized. Here, using a peptide fishing assay and...
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Full title
Complex of HIV-1 Integrase with Cellular Ku Protein: Interaction Interface and Search for Inhibitors
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8951179
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8951179
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms23062908
