A proteome-wide atlas of lysine-reactive chemistry
A proteome-wide atlas of lysine-reactive chemistry
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Recent advances in chemical proteomics have begun to characterize the reactivity and ligandability of lysines on a global scale. Yet, only a limited diversity of aminophilic electrophiles have been evaluated for interactions with the lysine proteome. Here, we report an in-depth profiling of >30 uncharted aminophilic chemotypes that greatly expands...
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A proteome-wide atlas of lysine-reactive chemistry
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8952960
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8952960
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ISSN
1755-4330
E-ISSN
1755-4349
DOI
10.1038/s41557-021-00765-4
