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MGP promotes CD8 + T cell exhaustion by activating the NF-κB pathway leading to liver metastasis of...

MGP promotes CD8 + T cell exhaustion by activating the NF-κB pathway leading to liver metastasis of...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8990480

MGP promotes CD8 + T cell exhaustion by activating the NF-κB pathway leading to liver metastasis of colorectal cancer

About this item

Full title

MGP promotes CD8 + T cell exhaustion by activating the NF-κB pathway leading to liver metastasis of colorectal cancer

Publisher

Australia: Ivyspring International Publisher Pty Ltd

Journal title

International journal of biological sciences, 2022-01, Vol.18 (6), p.2345-2361

Language

English

Formats

Publication information

Publisher

Australia: Ivyspring International Publisher Pty Ltd

More information

Scope and Contents

Contents

Matrix Gla protein (MGP) was originally reported as a physiological suppressor of ectopia calcification and has also been reported to be associated with cancer. However, the relation between the biological functions of MGP and the immune response in colorectal cancer (CRC) remains unclear. Here, we investigated the regulatory role of MGP in the imm...

Alternative Titles

Full title

MGP promotes CD8 + T cell exhaustion by activating the NF-κB pathway leading to liver metastasis of colorectal cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8990480

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8990480

Other Identifiers

ISSN

1449-2288

E-ISSN

1449-2288

DOI

10.7150/ijbs.70137

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