A Review of the Recent Developments of Molecular Hybrids Targeting Tubulin Polymerization
A Review of the Recent Developments of Molecular Hybrids Targeting Tubulin Polymerization
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Microtubules are cylindrical protein polymers formed from αβ-tubulin heterodimers in the cytoplasm of eukaryotic cells. Microtubule disturbance may cause cell cycle arrest in the G2/M phase, and anomalous mitotic spindles will form. Microtubules are an important target for cancer drug action because of their critical role in mitosis. Several microt...
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Full title
A Review of the Recent Developments of Molecular Hybrids Targeting Tubulin Polymerization
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8999808
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8999808
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms23074001
