Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithe...
Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition
About this item
Full title
Author / Creator
Carraro, Gianni , Langerman, Justin , Sabri, Shan , Lorenzana, Zareeb , Purkayastha, Arunima , Zhang, Guangzhu , Konda, Bindu , Aros, Cody J. , Calvert, Ben A. , Szymaniak, Aleks , Wilson, Emily , Mulligan, Michael , Bhatt, Priyanka , Lu, Junjie , Vijayaraj, Preethi , Yao, Changfu , Shia, David W. , Lund, Andrew J. , Israely, Edo , Rickabaugh, Tammy M. , Ernst, Jason , Mense, Martin , Randell, Scott H. , Vladar, Eszter K. , Ryan, Amy L. , Plath, Kathrin , Mahoney, John E. , Stripp, Barry R. and Gomperts, Brigitte N.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Cystic fibrosis (CF) is a lethal autosomal recessive disorder that afflicts more than 70,000 people. People with CF experience multi-organ dysfunction resulting from aberrant electrolyte transport across polarized epithelia due to mutations in the cystic fibrosis transmembrane conductance regulator (
CFTR
) gene. CF-related lung disease is by...
Alternative Titles
Full title
Transcriptional analysis of cystic fibrosis airways at single-cell resolution reveals altered epithelial cell states and composition
Authors, Artists and Contributors
Author / Creator
Langerman, Justin
Sabri, Shan
Lorenzana, Zareeb
Purkayastha, Arunima
Zhang, Guangzhu
Konda, Bindu
Aros, Cody J.
Calvert, Ben A.
Szymaniak, Aleks
Wilson, Emily
Mulligan, Michael
Bhatt, Priyanka
Lu, Junjie
Vijayaraj, Preethi
Yao, Changfu
Shia, David W.
Lund, Andrew J.
Israely, Edo
Rickabaugh, Tammy M.
Ernst, Jason
Mense, Martin
Randell, Scott H.
Vladar, Eszter K.
Ryan, Amy L.
Plath, Kathrin
Mahoney, John E.
Stripp, Barry R.
Gomperts, Brigitte N.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9009537
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9009537
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-021-01332-7