Rapid pathogen detection by metagenomic next-generation sequencing of infected body fluids
Rapid pathogen detection by metagenomic next-generation sequencing of infected body fluids
About this item
Full title
Author / Creator
Gu, Wei , Deng, Xianding , Lee, Marco , Sucu, Yasemin D. , Arevalo, Shaun , Stryke, Doug , Federman, Scot , Gopez, Allan , Reyes, Kevin , Zorn, Kelsey , Sample, Hannah , Yu, Guixia , Ishpuniani, Gurpreet , Briggs, Benjamin , Chow, Eric D. , Berger, Amy , Wilson, Michael R. , Wang, Candace , Hsu, Elaine , Miller, Steve , DeRisi, Joseph L. and Chiu, Charles Y.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
We developed a metagenomic next-generation sequencing (mNGS) test using cell-free DNA from body fluids to identify pathogens. The performance of mNGS testing of 182 body fluids from 160 patients with acute illness was evaluated using two sequencing platforms in comparison to microbiological testing using culture, 16S bacterial PCR and/or 28S–intern...
Alternative Titles
Full title
Rapid pathogen detection by metagenomic next-generation sequencing of infected body fluids
Authors, Artists and Contributors
Author / Creator
Deng, Xianding
Lee, Marco
Sucu, Yasemin D.
Arevalo, Shaun
Stryke, Doug
Federman, Scot
Gopez, Allan
Reyes, Kevin
Zorn, Kelsey
Sample, Hannah
Yu, Guixia
Ishpuniani, Gurpreet
Briggs, Benjamin
Chow, Eric D.
Berger, Amy
Wilson, Michael R.
Wang, Candace
Hsu, Elaine
Miller, Steve
DeRisi, Joseph L.
Chiu, Charles Y.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9020267
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9020267
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-020-1105-z
