Self-guarding of MORC3 enables virulence factor-triggered immunity
Self-guarding of MORC3 enables virulence factor-triggered immunity
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Full title
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Pathogens use virulence factors to inhibit the immune system
1
. The guard hypothesis
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,
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postulates that hosts monitor (or ‘guard’) critical innate immune pathways such that their disruption by virulence factors provokes a secondary immune response
1
. Here we describe a ‘self-guarded’ immune pathway in human monocytes, i...
Alternative Titles
Full title
Self-guarding of MORC3 enables virulence factor-triggered immunity
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9045311
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9045311
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-021-04054-5
